产品货号：
Z27699
中文名称：
SRCIN1抗体
英文名称：
Anti-SRCIN1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SRCIN1 Antibody |
| 指标别名 | SRC kinase signaling inhibitor 1;P140;SNIP;SRCIN1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,IHC-F,ICC,FCM,ELISA |
| 基因名称 | SRCIN1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human SRCIN1 recombinant protein (Position:E189-E287). |
| 实际分子量 | 140KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Using yeast 2-hybrid analysis,protein pull-down assays,and mutation analysis,it is showed that the first coiled-coil domain of rat Snip interacted with the N-terminal t-SNARE domain of Snap25 (600322).Biochemical studies demonstrated that Snip was tightly associated with rat brain cytoskeleton.Indirect immunofluorescence and confocal microscopy of rat PC12 pheochromocytoma cells revealed colocalization of Snip with Snap25 in the actin cytoskeleton,particularly in filopodia,lamellipodia,and neuritic extensions,including the tips.Overexpression of Snip or its Snap25-interacting domain inhibited calcium-dependent exocytosis from PC12 cells.It is concluded that SNIP is involved in regulation of neurosecretion,perhaps via its interaction with SNAP25 and the cytoskeleton. |
| Uniprot ID | Q9C0H9 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunohistochemistry in frozen section 1:50～400 Immunocytochemistry in fixed cells 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (ELISA)： 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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